cardiac function — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15052	Dapansutrile		NOD-like Receptor (NLR) , NOD
	Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.		NOD-like Receptor (NLR) , NOD
T15050	Danicamtiv	MYK-491,SAR 440181	Myosin
	Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.		Myosin
TP2058L	Catestatin acetate	Catestatin acetate(142211-96-9 free base)	Endogenous Metabolite , AChR
	Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release. Catestatin acetate regulates cardiac function and blood pressure.		Endogenous Metabolite , AChR
T31640	Enrasentan	SB-217242,SB 217242,SB217242	Endothelin Receptor
	Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure, prevents cardiac hypertrophy, and protects myocardial function.		Endothelin Receptor
TCO2745	Cyclic AMP	Adenosine 3',5'-cyclophosphate,cAMP,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate	Others , Endogenous Metabolite
	Cyclic AMP (cAMP) (Adenosine 3',5'-cyclophosphate) combined with vitamin C treatment of children with viral myocarditis has exact curative effect, and it can improve cardiac function of patients and improve immune functi...		Others , Endogenous Metabolite
T9232	Mitochondrial fusion promoter M1		Mitochondrial Metabolism
	Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...		Mitochondrial Metabolism
T2750	Ginkgolide C	BN-52022	MMP , Sirtuin , Endogenous Metabolite , AMPK
	Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.		MMP , Sirtuin , Endogenous Metabolite , AMPK
T68037L	CBS-1114 HCl	N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base)	Lipoxygenase
	CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl maintains and improves cardiac function, attenuates cardiac d...		Lipoxygenase
T14875	Indocyanine green	Cardiogreen,IC Green,Foxgreen	Others
	Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and fo...		Others
TP1937L1	RFRP-1 (human) acetate(311309-25-8 free base)		Neuropeptide Y Receptor
	RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduc...		Neuropeptide Y Receptor
T36569	KR-32568		Sodium Channel
	KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM). KR-32568 exhibits potent cardioprotective effects. When used at a concentration of 10 μM, it restored cardiac systolic function in an isolated i...		Sodium Channel
T3893	Forsythoside B		TNF , NF-κB
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...		TNF , NF-κB
T33451	ML 7	ML7,ML-7
	ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury.
T70699	SAR296968
	SAR296968 is a novel selective NCX inhibitor, improving cardiac function and restoring sympathovagal balance in heart failure.
T16332	NKH477	Colforsin dapropate hydrochloride	NMDAR
	NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cyt...		NMDAR
T75947	RFRP-1(human) TFA
	RFRP-1(human) TFA, an endogenous NPFF receptor agonist, exhibits potent activity with EC50 values of 0.0011 nM for NPFF2 and 29 nM for NPFF1. It significantly diminishes the contractile function of isolated rat and rabbi...
TP1937	RFRP-1(human)	RFRP-1 (human)
	Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume...
T70280	KB-R7785
	KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) model by inhibiting the proteolytic activation of HB-EGF signaling, exerting its antidiabetic effect b...
TP1827L	Neuronostatin-13 human acetate	Neuronostatin-13 human acetate(1096485-24-3 free base)	Others
	Neuronostatin-13 human acetate is a 13-amino acid peptide hormone, which plays an important role in the regulation of hormonal and cardiac function.		Others
T60377	CXL-1020
	CXL-1020, a nitroxyl (HNO) prodrug, enhances cardiac inotropy/lusitropy and Ca 2+ cycling in rats exhibiting abnormal relaxation, induces vasorelaxation, and augments cardiac function in canine models. It has been invest...